How polynerve works
Polynerve works by creating an artificial pathway that guides nerve fibres across the gap between severed nerve endings (caused by an accident) and muscle or skin.
This physical guidance is extremely important to nerve regeneration. To provide it, the Polynerve team has developed novel grooves within the conduit’s inner lumen. These align Schwann cells (the supportive cell of the peripheral nerve) and direct them across the gap, maximising the regeneration potential.
THE NEED FOR AN ALTERNATIVE APPROACH
Bioengineered grooves for Schwann cell alignment and direction
The Polynerve conduit
With non-grooved polymer, Schwann cells have no alignment or direction, which reduces the potential for regeneration.
With Polynerve grooved conduits, Schwann cells are aligned and directed, leading to improved repair of severed nerves.